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NEW ISSUE

Dear Colleague,

We are delighted to announce the publication of Volume 7, Issue 4 of Bladder Cancer (BLC). This issue hosts an outstanding selection of content, including an editorial, five research articles, and two systematic reviews. From the editors of the regular journal sections, there are also new Challenging Case, Clinical Trials Corner, and Paper Alert contributions. All content is freely accessible and can be can be viewed via the links below. Also enclosed is news from the Bladder Cancer Advocacy Network and a selection of our top viewed recent articles. We are also pleased to welcome Rebecca Barasky who has joined the board in the position of Associate Editor.

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Call for Papers

As a member of our research community, we would like to invite you to contribute your own research articles to Bladder Cancer, which offers contributing authors many benefits:

• First class Editorial Board
• Rigorous peer review and speedy manuscript processing
• Rapid online publication (pre-press)

Submit your manuscript online via Editorial Manager
View detailed Instructions to Authors
Aims and Scope

We look forward to working with you.

Best wishes,

Editors-in-Chief

Seth P. Lerner, MD
Scott Department of Urology
Baylor College of Medicine
Houston, Texas, USA
Email: blc@iospress.com

Dan Theodorescu, MD, PhD
Samuel Oschin Comprehensive Cancer Institute
Cedars-Sinai Medical Center
Los Angeles, California, USA
Email: blc@iospress.com

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All content is currently freely available online to all readers

EDITORIAL
The Pros and Cons of “Machination of Medicine” in Genitourinary Oncology PracticeOpenly Available
Pederzoli, Filippo | Bandini, Marco | Raggi, Daniele | Ross, Jeffrey S. | Spiess, Philippe E. | Necchi, Andrea

BRIEF REPORT
CD274 (PD-L1) Copy Number Changes (Gain) & Response to Immune Checkpoint Blockade Therapy in Carcinomas of the Urinary TractOpenly Available
Gupta, Sounak | Vanderbilt, Chad M. | Zhang, Yanming | Tickoo, Satish K. | Fine, Samson W. | Gopalan, Anuradha | Chen, Ying-Bei | Sirintrapun, Sahussapont J. | Teo, Min Yuen | et al.

RESEARCH ARTICLES
Impact of Neoadjuvant Chemotherapy for Upper Tract Urothelial Carcinoma: A Population Based AnalysisOpenly Available
Venkat, Siv | Lewicki, Patrick J. | Basourakos, Spyridon P. | Scherr, Douglas S.

Real-World Study of Treatment with Pembrolizumab Among Patients with Advanced Urothelial Tract Cancer in DenmarkOpen Access
Omland, Lise Høj | Stormoen, Dag Rune | Dohn, Line Hammer | Carus, Andreas | Als, Anne Birgitte | Jensen, Niels Viggo | Taarnhøj, Gry Assam | Tolver, Anders | Pappot, Helle

Safety and Pharmacokinetics of Intravesical Chitosan/Interleukin-12 Immunotherapy in Murine BladdersOpen Access
Nguyen, Khue G. | Wagner, Ethan S. | Vrabel, Maura R. | Mantooth, Siena M. | Meritet, Danielle M. | Zaharoff, David A.

Cost of Care in Open Cystectomy Patients Across Time and Space: Does it matter?Openly Available
Sun, Helen H. | Prunty, Megan | Isali, Ilaha | Mahran, Amr | Ginsburg, Kevin | Markt, Sarah | Ponsky, Lee | Calaway, Adam | Bukavina, Laura

SYSTEMATIC REVIEWS
Optimizing Nutritional Status in Patients Undergoing Radical Cystectomy: A Systematic Scoping ReviewOpen Access
Alam, Syed M. | Michel, Carrie | Robertson, Hilary | Camargo, Juliana T. | Linares, Brenda | Holzbeierlein, Jeffrey | Hamilton-Reeves, Jill M.

Quality of Life following Chemoradiotherapy for Localized Muscle Invasive Bladder Carcinoma: A Systematic ReviewOpenly Available
de Ruiter, Ben-Max | Keijzer, Abel N. | Hulshof, Maarten C.C.M. | Bins, Adriaan D. | de Reijke, Theo M. | Oddens, Jorg R.

OTHER CONTENT
Challenging Cases in Urothelial Cancer: Case 22Openly Available
Soloway, Mark S.

Clinical Trials Corner Issue 7(4)Openly Available
Agarwal, Piyush K. | Sternberg, Cora N.

Paper Alert: Salvage for BCG Unresponsive and Recurrent DiseaseOpenly Available
Messing, Edward M.

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Bladder Cancer News

BLC news square

New Associate Editor: Rebecca Barasky, MPH

We are pleased to welcome Rebecca Barasky, MPH to the Bladder Cancer editorial board in the position of Associate Editor. As BCAN’s Director of Research, Rebecca is responsible for the day-to-day operational oversight and management of all grant activities including application solicitation, grants management, investigator support, and analysis of program efficiency. Rebecca also manages BCAN grants from pre-award through award close-out while working closely with BCAN’s senior management to successfully achieve desired research outcomes.

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BCAN to Offer Two Bladder Cancer Research Innovation Awards in 2022

The Bladder Cancer Advocacy Network (BCAN) will offer two Bladder Cancer Research Innovation Awards in 2022. This marks the second consecutive year that BCAN will grant two such awards to support experienced investigators with exceptionally novel and creative projects designed to produce significant advances in our understanding of the management of bladder cancer. Both awarded proposals will be funded for US$300,000 for two years.

These awards support high risk, high reward projects with great potential to produce breakthroughs in our understanding of bladder cancer. The proposed research may be basic, translational, clinical or epidemiological and must have direct applicability and relevance to bladder cancer. Applications must include innovative approaches and new ideas to be eligible for funding.

Deadline for submission of Letter of Intent: January 12, 2022

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Most Viewed BLC Articles in Q4 2021

Listing articles published only in 2020 & 2021 so you can read the most popular recent content

In the World of Bladder Tumors: Size Does Matter (Research Article in Vol.6, Iss.2, 2020)
Loloi, Justin | Allen, Jordan L. | Schilling, Amber | Hollenbeak, Christopher | Merrill, Suzanne B. | Kaag, Matthew G. | Raman, Jay D.

Histologic Variants of Urothelial Carcinoma: Morphology, Molecular Features and Clinical Implications (Review Article in Vol.6, Iss.2, 2020)
Alderson, Meera | Grivas, Petros | Milowsky, Matthew I. | Wobker, Sara E.

FGFR3 – a Central Player in Bladder Cancer Pathogenesis? (Review Article in Vol.6, Iss.4, 2020)
Knowles, Margaret A.

Plasmacytoid Urothelial Carcinoma: Response to Chemotherapy and Oncologic Outcomes (Research Article in Vol.6, Iss.1, 2020)
Diamantopoulos, Leonidas N. | Khaki, Ali Raza | Grivas, Petros | Gore, John L. | Schade, George R. | Hsieh, Andrew C. | Lee, John K. | Yezefski, Todd | Yu, Evan Y. | Schweizer, Michael T. | et al.

Cost of Care in Open Cystectomy Patients Across Time and Space: Does it matter? (Research Article in Vol.7, Iss.4, 2021)
Sun, Helen H. | Prunty, Megan | Isali, Ilaha | Mahran, Amr | Ginsburg, Kevin | Markt, Sarah | Ponsky, Lee | Calaway, Adam | Bukavina, Laura

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